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InfraVis@LU

InfraVis is a Swedish national Research Infrastructure for data visualization. InfraVis helps you visualize research data from any scientific domain and gives you access to state-of-the-art visualization competence, support, equipment, training, and methods. InfraVis@LU is the InfraVis node for Visualisation and Analysis at Lund University, coordinated by CIPA.   InfraVis provides advanced visuali

https://www.microscopy.lu.se/cipa/infravislu - 2025-12-13

CryoEM for Life Sciences at Lund University

ServicesCryoEM at Lund University has a sample preparation lab installed with Mark IV Vitrobot (Thermo Fisher) to prepare cryo grids. Samples can be prescreened by a negative stain, and the cryo grids can be shipped to SciLifeLab or other facilities. In the beginning of 2025 there will also be a state of the art Glacios2 cryo electron microscope with a direct electron detector Falcon4i in our faci

https://www.microscopy.lu.se/cryoem-life-sciences-lund-university - 2025-12-13

cryoEM applications experts

Welcome to contact one of our experts! Crispin Hetherington Crispin’s background is transmission electron microscopy in materials science. In his various job positions in microscope user facilities, he gained a wide experience of different samples and of microscopy techniques including high resolution and aberration correction in TEM and STEM.  His present role in nCHREM now mainly involves operat

https://www.microscopy.lu.se/single-particle-cryoem-0/cryoem-applications-experts - 2025-12-13

cryoEM infrastructure stakeholders

Lotta Happonen I work as a researcher at the Faculty of Medicine studying protein-protein complexes arising at the host-pathogen interface, with the aim of understanding how pathogens evade the human immune defence. The main methods we are using are quantitative and structural mass spectrometry (cross-linking and hydrogen-deuterium exchange) in combination with single-particle cryo-EM. Since its s

https://www.microscopy.lu.se/single-particle-cryoem-0/cryoem-infrastructure-stakeholders - 2025-12-13

start

Leading research in psychological defence About the institute... The Lund University Psychological Defence Research Institute (Forskningsinstitutet för psykologiskt försvar) is a multidisciplinary research unit within the Department of Communication. Our work focuses on the theory and practice of psychological defence, with a focus on research into analyzing and countering hostile information infl

https://www.psychologicaldefence.lu.se/start - 2025-12-13

About the institute

The Lund University Psychological Defence Research Institute (Forskningsinstitutet för psykologiskt försvar) is a multidisciplinary research unit within the Department of Communication. Our work focuses on the theory and practice of psychological defence and research into analyzing and countering hostile information influence operations and hybrid threats. The purpose of psychological defence is t

https://www.psychologicaldefence.lu.se/about-institute - 2025-12-13

ADAC.io

Attribution – Data – Analysis – Countermeasures. InterOperability ADAC.io is a Horizon project coordinated by the Psychological Defence Research Institute As of 1 February 2024, the Psychological Defence Research Institute coordinates the Horizon project ADAC.io, engaging seven partners in a three-year-long project. Based on the concept of Foreign Information Manipulation & Interference (FIMI) as

https://www.psychologicaldefence.lu.se/adacio - 2025-12-13

Research

Below are some of the main publications by the Psychological Defence Research Institute and our affiliates. 2025Falkheimer, J. & Pamment, J. (2025). The dark and unexplored side of strategic communication – information influence on video game platforms. In Bowen, S. & Erzikova. E. Handbook of Innovations in Strategic Communication: AI, Futurism and Directions. Cheltenham: Edward Elgar PublishingPa

https://www.psychologicaldefence.lu.se/research - 2025-12-13

Anna Blom Research Group

The Medical Protein Chemistry research group headed by prof. Anna Blom is located at the Wallenberg Laboratory within Skåne University Hospital in Malmö. The group is focused on the complement system in health and disease. Our ambition is to make high quality basic science based on clinically relevant questions and yielding novel diagnostic approaches and clinical interventions. Our research is su

https://www.protein-chemistry.lu.se/anna-blom-research-group-0 - 2025-12-13

Protein Chemistry Research Group

The Medical Protein Chemistry research group headed by prof. Anna Blom is located at the Wallenberg Laboratory within Skåne University Hospital in Malmö.  The group is focused on the complement system in health and disease. The complement, crucial part of innate immune system is involved in many basic biological processes such as defence against infections but when activated in a wrong place or no

https://www.protein-chemistry.lu.se/protein-chemistry-research-group - 2025-12-13

Top publications

Best publications from our group over past years. King B.C., Kulak K, Krus U., Rosberg R., Golec E., Wozniak K., Gomez M.F., Zhange E., O'Connell D., Renström E. and Blom A.M. (2019) Complement C3 proteinst against autophagy related beta-cell detah via ATG16L1 interaction and regulation of autophagy., Cell Metabolism, 29, 202-210.Kulak K., Kuska K., Colineau L., Mckay M., Maziarz K., Slaby J., Blo

https://www.protein-chemistry.lu.se/top-publications - 2025-12-13

Selected publications from the group

List of selected publications from our research group exemplifying the projects we are conducting. Blom. A. M., Pertoft H. and Fries E. (1995) Inter-a-inhibitor is required for the formation of the hyaluronan-containing coat on fibroblasts and mesothelial cells. J. Biol. Chem., 270, 9698-9701. Blom A. M., Mörgelin M., Öyen M., Jarvet J. and Fries E. (1999) Structural characterization of inter-a-in

https://www.protein-chemistry.lu.se/top-publications/selected-publications-group - 2025-12-13

Projects

In blood, complement proteins are a major component and perhaps therefore most of these were identified already decades ago. However, only in recent years it has become apparent that complement not only plays a major role in innate defense against pathogens but also identifies foreign materials and removes waste (immune complexes and dying cells). The physiological relevance of complement is demon

https://www.protein-chemistry.lu.se/projects - 2025-12-13

Insulin and Immunity: when complement takes control

We are studying an unexpected role of complement – in the physiology and metabolism of pancreatic beta-cells. Surprisingly, this is related to intracellular functions of complement and therefore changes the way we perceive this “blood” system and will likely inspire discovery of many other intracellular effects of complement. We study the role of intracellular complement factor C3 and membrane bou

https://www.protein-chemistry.lu.se/projects/insulin-and-immunity-when-complement-takes-control - 2025-12-13

Bacterial complement evasion strategies

As a first line of defense against pathogens and a mediator between innate and adaptive immunity, complement is a particular focus of evasion strategies developed by pathogens.  We showed that one common strategy is to bind complement inhibitor C4BP, which leads to decreased opsonisation of bacteria with C3b impairing phagocytosis and allowing bacterial survival. It appears that binding of C4BP is

https://www.protein-chemistry.lu.se/projects/bacterial-complement-evasion-strategies - 2025-12-13

Pathologic complement activation in diseases

  Misguided or excessive complement activation is involved in many common diseases such as rheumatoid arthritis, systemic lupus erythematosus, vasculitis and age-related macula degeneration. In collaboration with clinicians we are studying molecular mechanisms of complement involvement in these diseases. Joint inflammation in rheumatoid arthritis (RA), a common chronic inflammatory disease that ca

https://www.protein-chemistry.lu.se/projects/pathologic-complement-activation-diseases - 2025-12-13

Complement and cancer

Complement-dependent cytotoxicity is one of the mechanisms by which therapeutic monoclonal antibodies are toxic to cancer cells. Also, complement is currently undergoing re-appreciation of its role in the immune surveillance of tumors. The majority of human tumors are low immunogenic and complement may be involved in their recognition via direct “danger signal” elicited activation. This in turn at

https://www.protein-chemistry.lu.se/projects/complement-and-cancer - 2025-12-13

Inherited deficiencies of complement inhibitors

Complement has recently gained substantial worldwide attention, as it was discovered that several common diseases such as age-related macular degeneration (blindness in elderly) are related to deregulation of the balance between complement activation and inhibition. Full complement deficiencies lead to severe infectious and autoimmune diseases but are uncommon while it appears that we are just beg

https://www.protein-chemistry.lu.se/projects/inherited-deficiencies-complement-inhibitors - 2025-12-13